On screen
Cast
79 credited performers
Mark Ruffalo
Dominick Birdsey / Thomas Birdsey
Melissa Leo
Concettina Ipolita Tempesta 'Ma' Birdsey
Rosie O'Donnell
Lisa Sheffer
Archie Panjabi
Dr. Patel
Kathryn Hahn
Dessa Constantine
John Procaccino
Ray Birdsey
Rob Huebel
Leo
Michael Greyeyes
Ralph Drinkwater
Gabe Fazio
Shawn Tudesco / Dominick and Thomas Acting Double
Rocco Masihi
Young Thomas Birdsey
Donnie Masihi
Young Dominick Birdsey
Laura Esterman
Ruth Hood
Imogen Poots
Joy Hanks
Bruce Greenwood
Dr. Hume
Marcello Fonte
Domenico Onofrio Tempesta
Annie Fitzgerald
Miss Hanker
Joseph Ragno
Henrey Hood
Acahkos Johnson
Penny Ann Drinkwater
Jaiden Klein
Marie Sexton
Charlie Reina
Channy
Violet Adams
Bunny Borsa
Oliver Patnode
Otero
Matt Helm
Young Leo
Derek Goh
17-19 Year Old Dominick & Thomas Acting Double
Agatha Nowicki
Angie Constantine
Irene Muscara
Prosperina Tucci
Adrienne R. Williams
Mrs. Birdsall
Tatanka Means
Nabby Drinkwater
Philip Ettinger
Early Adulthood Dominick Birdsey / Thomas Birdsey
Aisling Franciosi
Young Dessa Constantine
Juliette Lewis
Nedra Frank
Harris Yulin
Father Lavie
Sue Jean Kim
Dr. Yup
Michael Simon Hall
Stuart Feinstein
Gina Costigan
Mrs. O'Meara
Steven Cox
Boyfriend of Dr. Hume's Daughter
MorningStar Angeline
Nabby Drinkwater's Wife
Al Linea
Abruzzi
Richard Fitch
Mill Foreman
Amy Lynn Stewart
Merciful Mother
Guillermo Díaz
Sergeant Mercado
Marylouise Burke
Librarian
Brian Goodman
Al
Sandra Berrios
Social Worker at Hatch
Laura Silverman
Kristin
Christine Parks
Humanities Department Chair
Morgan Sullivan
Office Buddy
Jake Robards
Landlubbers (voice)
Michael Genet
Thomas' Surgeon
María Gonzalez
Ma's Oncology Nurse
A.C. Peterson
Gene Diogenes
Christopher J. Hanke
Thad
James Quattrochi
Bus Driver
Rachel B. Joyce
Jeanette
Paul Coleman
Support Group Counselor
Brandon J. Dirden
Kyle's Dad
Katt Masterson
Doreen
Jason Furlani
Larry Penn
Kate Grimes
English Professor
Chelsea Sheets
Brunette
Felix Solis
Nurse
Joe Grifasi
Steve Falice
Raymond Neil Hernandez
Omar
Simone Coppo
Vincenzo Tempesta
Sean Cullen
Dr. Yates
Federico Dordei
Nunzio Tucci
Shannon Plumb
Charlotte
Zaria Degenhardt
11 Year Old Concettina
Mark A. Gamma
Mourner Mark
Wayne J. Miller
Mourner Wayne
Thomas Gionet-Lavigne
Ray's Orderly
Alexander Hacker
Templeton
Robert Mladinich
Paddy Wagon Officer
Destry Allyn Spielberg
Dr. Hume's Daughter
Roberta Riganò
Ignazia Tempesta
Tim Ruddy
Robocop
Ethan Crystal
Thin Sailor
James Pravasilis
Third Guard
Michael Armand DeMatteo
Fatso