On screen
Cast
92 credited performers
Neil deGrasse Tyson
Self - Host
Ann Druyan
Character not listed
Carl Sagan
Self (archive footage)
Seth MacFarlane
Giordano Bruno (voice)
Sasha Sagan
Rachel Molly Gruber
Stoney Emshwiller
Character not listed
André Sogliuzzo
Christopher Wren (voice)
Christopher Emerson
Character not listed
Piotr Michael
Edmund Muskie (voice)
Enn Reitel
Henry Norris Russell (voice)
Keythe Farley
Character not listed
Patrick Stewart
William Herschel (voice)
Elizardo Torrez
Young Carl Sagan
Trang Vo
(voice)
John Steven Rocha
Bellaramine (voice)
Paul Telfer
Angry Scholar #2 (voice)
Jonathan Morgan Heit
John Herschel (voice)
Cary Elwes
Edmond Halley / Robert Hooke (voice)
Tom Konkle
Samuel Pepys (voice)
Alexander Siddig
Isaac Newton (voice)
Alfred Molina
Ibn al-Haytham (voice)
Richard Gere
Clair Patterson (voice)
Marc Worden
Harrison Brown (voice)
Kirsten Dunst
Cecilia Payne (voice)
Marlee Matlin
Annie Jump Cannon (voice)
Peggy Jo Jacobs
Margaret Harwood (voice)
Amanda Seyfried
Marie Tharp (voice)
Christiane Amanpour
Enheduanna (voice)
Michael Chochol
Jan Oort
Oliver Vaquer
Joseph von Fraunhofer (voice)
Fred Tatasciore
Democritus (voice)
Larry Cedar
Character not listed
Nick Jameson
Character not listed
Michael McConnohie
Character not listed
Masasa Moyo
Character not listed
Maria Frucci
Character not listed
Martin Jarvis
Humphry Davy (voice)
Noah Langford
(voice)
Fay Masterson
(voice)
Heiko Obermöller
Einstein's Father (voice)
Julian Ovenden
Michael Faraday (voice)
Jack Rainsford
(voice)
Glenn Steinbaum
Bruce Heezen (voice)
William Salyers
(voice)
Paul Sorvino
Augustin Mouchot (voice)
Eliza Schneider
(voice)
Frank Baxter
Self (archive footage)
John F. Kennedy
Self (voice) (archive footage)
Masoumeh Husseini
Monk (voice)
Harssh A. Singh
Ashoka (voice)
Nick Sagan
Character not listed
Clinnette Minnis
Character not listed
Shereen Balles
Female Voyager (voice)
Kapeneta Te'o-Tafiti
Male Voyager (voice)
Joseph Grange
John Herschel (voice)
Carol Bach Rita
Caroline Herschel (voice)
Viggo Mortensen
Nikolai Vavilov (voice)
Ken Lally
(voice)
Phil Crowley
(voice)
Yuri Lowenthal
(voice)
Edita Brychta
(voice)
Christopher Lee Parson
(voice)
Andrew Pifko
(voice)
Brendan Bradley
(voice)
Matthew Jayson Cwern
(voice)
Alan Shearman
(voice)
Natasha Goubskaya
(voice)
Skye Sammoutis
(voice)
Marcelo Tubert
(voice)
Mara Junot
(voice)
Rick Pasqualone
(voice)
Elijah Braik
(voice)
Novi Brown
(voice)
Jamie Hanes
Character not listed
Will Greenburg
John Goodricke
Dex de Groot
Character not listed
Joep Fellinger
Character not listed
Steve Oatway
Charles Darwin
Adam Tsekhman
Christiaan Huygens
Neil Arnote
Neil Armstrong
Ernie Vigil
Thomas Young
Judd Hirsch
Robert Oppenheimer (voice)
Olivia D'Abo
Marie Curie (voice)
Yurika Okamura
(voice)
Selyna Chan
(voice)
Sianna Chan
(voice)
Joseph J. Micucci
Young Father
Lennard Ortmann
Albert Einstein
Alex Bartram
Samuel Sagan
Brannon Braga
World's Fair Attendee
Marcello Guedes
Young Neil deGrasse Tyson
Leandro Guedes
Young Stephen Joseph Tyson