On screen
Cast
240 credited performers
Derek Waters
Self - Host / Various Characters
Bennie Arthur
Various
Maria Blasucci
Various
Craig Cackowski
Various
Jeremy J. Tutson
Various
Tymberlee Hill
Various
Sarah Burns
Various
Michael Daniel Cassady
Various
Adam Nee
Various
Jack McBrayer
Alan Freed
Mike Coleman
Various
Mort Burke
Various
Daryl J. Johnson
Robert S. Abbott
Jason Ritter
Stetson Kennedy
Tony Hale
Meriwether Lewis
Chris Parnell
Carl Sagan
Taran Killam
Frédéric Auguste Bartholdi
Colin Hanks
Ernest Thompson Seton
Jack Black
Elvis Presley
Johnny Knoxville
Ponce De Leon
Rich Fulcher
Porter Wagoner
Jesse Plemons
William Kenward
Kyle David Crosby
Scientist
Eric Edelstein
Himself - Narrator
Tim Baltz
Various
Aasha Davis
Various
Stephen Merchant
F**kin' President Lincoln
Jenny Slate
Herself - Storyteller
Michael Cera
Maurice Cohen
Natasha Leggero
Herself - Narrator
Bob Odenkirk
Richard Nixon
Rob Huebel
Governor Trevino
Georgia Hardstark
Herself - Narrator
Richard Riehle
James Roche
Ken Marino
Harry Houdini
Jaleel White
Bass Reeves
Alia Shawkat
Virginia Hall
Paul Scheer
Colonel Henry Ludington
Craig Anstett
Various
'Weird Al' Yankovic
Adolf Hitler
Kat Dennings
Sadie the Goat
Tommy Blacha
Self - Narrator
Will Ferrell
Roald Dahl
Nathan Fielder
John Lennon
Matt Walsh
Joseph Pulitzer
Tim Heidecker
Cop
Brett Gelman
Joseph Pulitzer
Lisa Bonet
Mary Ellen Pleasant
Terry Crews
Joe Louis
Seth Weitberg
Himself - Narrator
Mark Gagliardi
Himself - Narrator
Matt Gourley
Himself - Narrator
Chris Romano
Self - Narrator
Aubrey Plaza
Sacagawea
Allan McLeod
Himself - Narrator
Ben Folds
Self
Trace Lysette
Sylvia Rivera
Ron Funches
Herbert Muhammad
David Wain
Himself - Narrator
Emily Deschanel
Babe Didrikson
JT Palmer
Character not listed
Evan Rachel Wood
Mary Shelley
Zach Gilford
Jim Abbott
Adrianne Palicki
Kate Warne
Octavia Spencer
Harriet Tubman
Maestro Harrell
Louis Armstrong
Andre Royo
King Oliver
Jason Momoa
Jean Lafitte
Maya Rudolph
Griselda Blanco
Josh Hartnett
Clark Gable
Justin Long
Arno Penzias
Greg Kinnear
Thaddeus Lowe
Christopher Meloni
Othniel Marsh
Tess Lynch
Herself - Storyteller
Mark Proksch
Himself - Storyteller
Ellie Kemper
Nellie Bly
Haley Joel Osment
Kid Blink
Noah Wyle
Thomas Nast
Jason Alexander
William Tweed
Zach Woods
Lee Duncan
Ryan Phillippe
Benjamin Hayes
Giancarlo Esposito
Andrés Pico
Jason Mantzoukas
Pope
Patton Oswalt
Mac Brazel
Thomas Lennon
Major Marcel
Parker Posey
Mary Phelps Jacob
Henry Winkler
Zenas Fisk Wilber
Michael McKean
Carl Laemmle
Sam Rockwell
Bugsy Siegal
Donald Faison
Joe Louis
Dennis Quaid
Lucky Luciano
Nathan Fillion
Wernher von Braun
Chelsea Peretti
Ann Druyan
Adam Devine
Pavel Belyayev
Blake Anderson
Alexey Leonov
Liev Schreiber
Victor Lustig
Randall Park
Himself - Storyteller
Lyric Lewis
Character not listed
Aaron Takahashi
Frank Emi
Grant Imahara
Frank Inouye
Rachel Bloom
Herself - Storyteller
Kimiko Glenn
Maya Lin
Jon Gabrus
Himself - Storyteller
Jennie Pierson
Herself - Storyteller
Solomon Georgio
Himself - Storyteller
Shannon Woodward
Ida Tarbell
David Koechner
John Pastore
John Ennis
John D. Rockefeller
David Harbour
Vietnam Memorial Head
Kyle Mooney
Himself - Storyteller
Alison Rich
Herself - Storyteller
Kirsten Dunst
Agatha Christie
Jayma Mays
Florence Schaffner
Vanessa Bayer
Mary Gillespie
Claudia O'Doherty
Herself - Storyteller
Steven Weber
Lomax
Will Forte
Edwin Booth
Jonathan Ames
Junius Booth
Adam Scott
John Wilkes Booth
Dave Grohl
Memphis Mafia Member
Fred Willard
Deep Throat
Kyle Kinane
Self - Narrator
Joe Lo Truglio
Al Capone
Matt Besser
Edwin Stanton
Ike Barinholtz
August Spies
Charlie Finn
Cpt. 'Black Jack' Bonfield
Eric Filipkowski
Abraham Lincoln
Will Sasso
Frank Nitti
Moshe Kasher
Albert Parsons
James Atkinson
Himself - Narrator
Bill Hader
John Pemberton
Simon Helberg
Frank M. Robinson
Rob Riggle
J. Edgar Hoover
Lamorne Morris
Martin Luther King Jr.
Kevin Nealon
The Grand Dragon
Abdul Abukusumo
South American
Jen Kirkman
Herself - Narrator
Erin Rohr
Herself - Narrator
Michael Rohr
Himself - Narrator
Winona Ryder
Mary Dyer
Martin Starr
Art Thief
June Diane Raphael
Isabella Stewart Gardner
Connie Britton
Patricia Shaheen
Nick Offerman
Johnny Cool
Aidan Potter
Various
Zachary Burke
Various
Clint Culp
Policeman
Steve Berg
Various
Beth Cahill
Onlooker
Benjamin Poe
Policeman
Kaci Beeler
Herself - Interviewee
Artemis Pebdani
Herself - Narrator
Derrick Beckles
Himself - Narrator
Steve Little
Mark Twain
Ben Hoffman
Newscaster
Kristen Wiig
Patty Hearst
Ally Johnson
Herself
Paco Romane
Himself
Paget Brewster
Herself - Narrator
Lucius Dillon
Himself - Narrator
Jason Schwartzman
Ralph Nader
Owen Wilson
John Harvey Kellogg
Luke Wilson
Will Keith Kellogg
Alfred Molina
Sir Arthur Conan Doyle
Polly W. LePorte
Kellogg Patient
BJ Porter
Himself - Narrator
Alie Ward
Herself - Narrator
Kumail Nanjiani
Lakota Chief
Bradley Whitford
William Jennings Bryan
Casey Wilson
Dolly Parton
Dakota Black
Lakota Indian
A.J. Culp
Jolene
John A. Lorenz
Lakota Indian
Michael Kearney
Interviewee
Lacie Madison
Party Guest
Preston Flagg
Himself - Narrator
Timm Sharp
Billy the Kid
Andy Daly
Teddy Roosevelt
Jake Johnson
William B. Travis
Horatio Sanz
Gen. Santa Anna
Zach Paez
Various
Joseph Billingiere
Various
Raymond Ochoa
Various
Ricardo Tirado
Various
Dan Cooley
Rough Rider
Corey Weber
Tim- The Cowboy
Joseph Zinsman
Soldier
Mariah Iman Wilson
Claudette Colvin
Jerry Minor
Edgar Nixon
Jordan Peele
Percy Julian
Amber Ruffin
Herself - Narrator
Morgan Murphy
Herself - Narrator
Juno Temple
Sybil Luddington
Michaela Watkins
Nurse
Laura Dern
Nellie Bly
Eric Falconer
Himself - Narrator
Suzi Barrett
Herself - Narrator
J.D. Ryznar
Himself - Narrator
Lauren Lapkus
Normal Woman
Retta
Sylvia Robinson
Da'Vone McDonald
Big Bank Hank
Jon Daly
Kris Kristofferson
Colton Dunn
Himself - Narrator
Sophia Bush
Bonnie Raines
Jenna Fischer
Katharine Wright
Dave Foley
Alexis Pulaski
Ali Ghandour
Prince Aly Khan
Lin-Manuel Miranda
Himself
Questlove
Himself
Christopher Jackson
Himself
Anton Starkman
Character not listed
Alexandra Grey
Marsha P. Johnson
Paul Rust
John Wojtowicz
John Francis Daley
James J. Andrews
Collin Blair
Rusty Staubs
Ed Helms
William McMasters
Josh Charles
Jay Gould
Ronda Rousey
Gallus Mag
Hillary Anne Matthews
Self - Narrator
Drew Pinsky
Self - Guest Host
Duncan Trussell
Self - Narrator
Jon Lovett
Self - Narrator
Shiri Appleby
Margaret Howe Lovett
Brian Huskey
Dr. Max Jacobson
Greg Tuculescu
John F. Kennedy
Jay Duplass
Dr. John C. Lilly
Bruce M. Stockert
Man in Board Room
Samm Levine
Wayne Wheeler
Mary Elizabeth Ellis
Dorothy Fuldheim
Sam Richardson
Jim Brown
Aidan Sussman
Young Wayne Wheeler
George Wallace
Bill Russell
Lauren Sivan
Barbara Wallace
Echo Kellum
Lew Alcindor
Gaius Charles
Muhammad Ali
John Levenstein
Self - Narrator
Ashley Barnhill
Self - Narrator
Seth Rogen
Victor Frankenstein
Elijah Wood
Percy Shelley
Adam Campbell
George Soper