On screen
Cast
174 credited performers
Johnny Gilbert
Self - Announcer (voice)
Alex Trebek
Self - Host
Ken Jennings
Self
Mayim Bialik
Self - Host
Brad Rutter
Self
Mike Richards
Self - Host
Mehmet Oz
Self - Host
Aaron Rodgers
Self - Host
Anderson Cooper
Self - Host
Katie Couric
Self - Host
Bill Whitaker
Self - Host
Savannah Guthrie
Self - Host
Sanjay Gupta
Self - Host
Buzzy Cohen
Self - Host
Iain Armitage
Self - Clue Giver
Paolo Pasco
Self
Jamie Ding
Self
LeVar Burton
Self
Joe Buck
Self - Host
George Stephanopoulos
Self - Host
Robin Roberts
Self - Host
David Faber
Self - Host
Melissa Klapper
Self
Eric Jacobson
Bert / Grover / Oscar the Grouch (voice)
Kevin Olmstead
Self
Regis Philbin
Self
Stephen King
Self
Carol Burnett
Self
Keith Parrish
Self
Jonathan Hugendubler
Self
Ian Morrison
Self
Cheech Marin
Self
Jerry Orbach
Self
Peter Linz
Ernie (voice)
Ike Barinholtz
Self
Anne Hathaway
Self - Clue Presenter
Jason Alexander
Self - Clue Presenter
Michael Douglas
Self - Clue Presenter
Erik Charles Nielsen
Self
Donna Mills
Self
Andrew Shue
Self
Pat Sajak
Self - Guest Host
Anthony Daniels
Character not listed
Kenny Baker
Character not listed
Curt Schilling
Self
Sam Waterston
Self
James Denton
Self
Harry Shearer
Self
Harry Smith
Self
Joely Fisher
Self
Scott Turow
Self
Margaret Spellings
Self
Elizabeth Perkins
Self
Dean Stockwell
Self - Contestant
Lynn Redgrave
Self
Carson Kressley
Self
Doug Savant
Self
Christopher Meloni
Self
Neil Patrick Harris
Self
Isaac Mizrahi
Self
Miguel Ferrer
Self
Mario Cantone
Self
Paul Shaffer
Self
Michael McKean
Self
Aisha Tyler
Self
Emma Samms
Self
David Duchovny
Self
Jane Kaczmarek
Self
Bebe Neuwirth
Self
Soledad O'Brien
Self
Martin Short
Self
Hill Harper
Self
Melissa Joan Hart
Self
Alicia Witt
Self
Fred Savage
Self
Thomas Horn
Self - Contestant
Jacob Tremblay
Self - Clue Giver (voice)
Cameron Whiteside
Self - Contestant
Steven Silverman
Self - Contestant
Matt Ottinger
Self
Scheri Mullins
Self
Brett Kelly
Self - Contestant
Josh Jackson
Self
Caroline Paul
Self
Stacy Shelly
Self
Leslie Oakerson
Self
Andy Miller
Self
Jill Frechette
Self
Jeff Freymann
Self
Saralyn McKinnon-Crowley
Self
Seth Rogen
Self - Clue Presenter
Rose Byrne
Self - Clue Presenter
Luke Macfarlane
Self - Clue Presenter
Lindsay Lohan
Self - Clue Presenter
Jamie Lee Curtis
Self - Clue Presenter
Javier Bardem
Self - Clue Presenter
Adam Sandler
Self - Clue Presenter
James Gunn
Self - Clue Presenter
Gerard Butler
Self - Clue Presenter
Mason Thames
Self - Clue Presenter
Nico Parker
Self - Clue Presenter
Jon Hamm
Self - Clue Presenter
Olivia Munn
Self - Clue Presenter
Amanda Peet
Self - Clue Presenter
Dan Jansen
Self
Melody Thomas Scott
Self
Charles Shaughnessy
Self
Noah Wyle
Self
Charles Kimbrough
Self
Bill Maher
Self
Swoosie Kurtz
Self
Thomas Haden Church
Self
Yasmine Bleeth
Self
Jeff Foxworthy
Self
Alan Rachins
Self
Steven Weber
Self
Luke Perry
Self
Beau Bridges
Self
Judith Ivey
Self
Rosie O'Donnell
Self
Ed Begley Jr.
Self
Robert Guillaume
Self
Kathryn Erbe
Self
Tom Bergeron
Self
Jeri Ryan
Self
Sinbad
Self
Robin Quivers
Self
Mark McEwen
Self
Dan Cortese
Self
Ryan Dillon
Elmo (voice)
David Rudman
Cookie Monster (voice)
Jason Momoa
Self - Clue Presenter
Florence Pugh
Self - Clue Presenter
Andrew Garfield
Self - Clue Presenter
David Harbour
Self - Clue Presenter
Jay Thomas
Self
Tabitha Soren
Self
Susan Lucci
Self
Mark Messier
Self - Clue Presenter
Richard Jefferson
Self - Clue Presenter
Brendan Fraser
Self - Clue Presenter
Andrew Scott
Self - Clue Presenter
Jon Favreau
Self - Clue Presenter
Kareem Rahma
Self - Clue Presenter
Colin Jost
Self - Clue Presenter
Stanley Tucci
Self - Clue Presenter
Phil Lord
Self - Clue Presenter
Christopher Miller
Self - Clue Presenter
Gordon Ramsay
Self - Clue Presenter
Conan O'Brien
Self - Clue Presenter
Sam Heughan
Self - Clue Presenter
Mike Judge
Hank Hill (voice)
Pamela Adlon
Bobby Hill (voice)
Kathy Najimy
Peggy Hill (voice)
Zendaya
Self - Clue Presenter
Charlize Theron
Self - Clue Presenter
Lupita Nyong'o
Self - Clue Presenter
Harrison Ford
Self - Clue Presenter
Christa Miller
Self - Clue Presenter
Brett Goldstein
Self - Clue Presenter
Jessica Williams
Self - Clue Presenter
Jason Segel
Self - Clue Presenter
Olivia Rodrigo
Self - Clue Presenter
Tom Hanks
Self - Clue Presenter
Tim Allen
Self - Clue Presenter
Glen Powell
Self - Clue Presenter
Daisy Edgar-Jones
Self - Clue Presenter
Scarlett Johansson
Self - Clue Presenter
Jon Bon Jovi
Self - Clue Presenter
Tony Hale
Self - Clue Presenter
Sheryl Lee Ralph
Self - Clue Presenter
Chris Pratt
Self - Clue Presenter
Ellie Kemper
Self - Clue Presenter
W. Kamau Bell
Self