On screen
Cast
214 credited performers
George Lowe
Space Ghost (voice)
C. Martin Croker
Zorak / Moltar (voice)
Andy Merrill
Brak / Lokar (voice)
Dave Willis
Cyclo (voice)
James Kirkconnell
Kirk the Storyteller
Scott Finnell
Birdman (voice)
Don Kennedy
Character not listed
Bobcat Goldthwait
Character not listed
Judy Tenuta
Self
Conan O'Brien
Character not listed
Lori Fetrick
Character not listed
Steve Henneberry
Character not listed
David L. Lander
Character not listed
Peter Fonda
Character not listed
Buzz Aldrin
Character not listed
Merrill Markoe
Character not listed
Mark McEwen
Character not listed
Willie Nelson
Self
Steven Wright
Character not listed
Gary Owens
Gary (voice)
Isabel Gonzalez
Fran Drescher
John Henson
Self
Fred Willard
Self
Andy Dick
Self
Timothy Leary
Self
Cameron Diaz
Character not listed
Tyra Banks
Character not listed
Lee Meriwether
Self
Kathy Kinney
Character not listed
Kevin Smith
Character not listed
Alan Beckwith
Self
Carol Channing
Self
Bill Mumy
Self
Adam Carolla
Character not listed
Bob Denver
Self
David Cross
Character not listed
Joel Hodgson
Self
Schoolly D
Self
Catherine Bach
Self
Susan Olsen
Character not listed
Adam West
Self
Russell Johnson
Self
'Weird Al' Yankovic
Self
Susan Powter
Self
Tony Bennett
Self
Dawn Wells
Self
Ashley Judd
Self
Tom Arnold
Character not listed
Rob Zombie
Rob Zombie
Robin Gibb
Self
Barry Gibb
Self
Maurice Gibb
Self
Kevin Meaney
Self
Corri English
Galaxy Girl (voice)
Daryl Dragon
The Captain
Toni Tennille
Toni Tennille
Jerry Springer
Self
Sarah Jessica Parker
Self
Jon Schnepp
C. Ling Tile (voice)
Branford Marsalis
Self
Fran Drescher
Self
Alice Cooper
Self
Michael Stipe
Self
David Byrne
Self
Donny Osmond
Self
Jim Carrey
Self
Van Partible
Character not listed
Patrick A. Ventura
Character not listed
Craig McCracken
Character not listed
Genndy Tartakovsky
Character not listed
Eugene Mattos
Character not listed
Penn Jillette
Self
Teller
Self
Carrot Top
Self
Thurston Moore
Fred Cracklin
Jonathan Richman
Character not listed
Terry Jones
Self
Glen Phillips
Self
Bill Carter
Self
Joe Franklin
Self
Kamal Ahmed
Self
John G. Brennan
Self
Joyce Brothers
Self
Rich Hall
Self
Anka Radakovich
Self
Danny Bonaduce
Self
Sirajul Islam
Self
Mujibur Rahman
Self
Dennis Mehiel
Sal
Hulk Hogan
Self
Slash
Self
Sandra Bernhard
Self
B. Palmer Mills
Self
Matthew Sweet
Self
Michael Norman
Character not listed
Bill Nye
Self
Green Jellÿ
Character not listed
Cassandra Peterson
Elvira
Vinnie Dombroski
Character not listed
Jimmie Walker
Character not listed
Mike Watt
Character not listed
Dennis Diken
Character not listed
Pat DiNizio
Character not listed
Juliana Hatfield
Character not listed
Ben Folds
Character not listed
Wes Johnson
Character not listed
Robert Bakker
Character not listed
Matt Talbot
Character not listed
Method Man
Character not listed
Jill Cunniff
Self
Rodney Trevon Oliver
Character not listed
Rev. Norbert St. Louis
Character not listed
Les Claypool
Character not listed
Larry LaLonde
Character not listed
Matt Groening
Self
James Hetfield
Character not listed
Kirk Hammett
Character not listed
Janeane Garofalo
Character not listed
Flip Orley
Character not listed
Dave Grohl
Character not listed
John Popper
Character not listed
Emeril Lagasse
Character not listed
Nathalie Dupree
Character not listed
Martin Yan
Character not listed
Laurie Anderson
Character not listed
Steve Allen
Character not listed
Bob Odenkirk
Character not listed
Fred Schneider
Character not listed
Beck
Self
Robin Leach
Character not listed
Jimmy Cliff
Character not listed
Jack Logan
Character not listed
Maxcy Nolan
Character not listed
Mark Hamill
Self
Jon Stewart
Self
Michael McKean
Character not listed
Ice-T
Self
Ernie Cunnigan
Character not listed
Mike Judge
Self
Harland Williams
Self
Colin Quinn
Character not listed
Steve Smith
Red Green
Goldie Hawn
Character not listed
Tommy Davidson
Character not listed
George Clinton
Character not listed
Erik Estrada
Character not listed
Sam Butera
Character not listed
Michael Cudahy
Character not listed
Raven-Symoné
Self
Bob Goen
Character not listed
Charlton Heston
Self
Bob Abdou
Character not listed
Pete Michael
Character not listed
Russ Powell
Character not listed
Pat Boone
Character not listed
Chuck D
Character not listed
Paul Gilmartin
Character not listed
Annabelle Gurwitch
Character not listed
John Flansburgh
Character not listed
Ryah Rosenberg
Character not listed
Sean Medlock
Character not listed
Drew Pinsky
Character not listed
Marc Weiner
Character not listed
Greta Van Susteren
Character not listed
Garrett Morris
Character not listed
Bruce Hampton
Warren (voice)
Rebecca Romijn
Character not listed
Ben Stiller
Character not listed
Jim Jarmusch
Character not listed
Michael Moore
Character not listed
Joey Googe
Joey
Moby
Character not listed
Shirley Manson
Character not listed
Jeff Foxworthy
Character not listed
Denis Leary
Character not listed
Bob Costas
Character not listed
Al Roker
Character not listed
Isaac Hanson
Character not listed
Taylor Hanson
Character not listed
Zac Hanson
Character not listed
H. Jon Benjamin
Character not listed
Dave Thomas
Character not listed
Björk
Self
Thom Yorke
Character not listed
Busta Rhymes
Character not listed
Jack Black
Character not listed
Kyle Gass
Character not listed
Dennis Miller
Character not listed
Todd Barry
Character not listed
William Shatner
Character not listed
Jeff Probst
Character not listed
Robert Smigel
Triumph the Insult Comic Dog
Randy Poffo
Leonard Ghostal (voice)
Emo Philips
Character not listed
Joey Ramone
Self
Johnny Ramone
Self
Marky Ramone
Self
C. J. Ramone
Self
Cindy Guyer
Self
Dian Parkinson
Self
Eartha Kitt
Self
Chuck Russell
Self
Carl Clark
Carl the Cartoonist
Ken Osborne
Character not listed
Jefferson Clay
Zorak
Gus Jordan
Moltar
Sean Gooden
Bobcat Goldthwait
Derrick Slaugenhaupt
Bill Manspeaker
Scott Lipe
Michael Stipe
Rex Bullion
"Weird Al" Yankovic
Jacqueline Jusko
Your Mother (voice)
Amy Handler
Tooth Fairy (voice)
Bill Manspeaker
Character not listed
Penny Jones
Space Ghost's Mom (voice)