On screen
Cast
219 credited performers
Roseanne Barr
Roseanne Conner
John Goodman
Dan Conner
Sara Gilbert
Darlene Conner
Michael Fishman
D.J. Conner
Laurie Metcalf
Jackie Harris
Alicia Goranson
Becky Conner
Johnny Galecki
David Healy
Sarah Chalke
Becky Conner
Glenn Quinn
Mark Healy
Estelle Parsons
Beverly Harris
Natalie West
Crystal Anderson
Martin Mull
Leon Carp
Michael O'Keefe
Fred
Sandra Bernhard
Nancy
Tom Arnold
Arnie Thomas
Bonnie Bramlett
Character not listed
James Pickens Jr.
Chuck Mitchell
George Clooney
Character not listed
Shelley Winters
Nana Mary
Ames McNamara
Mark Conner-Healy
Jayden Rey
Mary Conner
Emma Kenney
Harris Conner-Healy
Ned Beatty
Ed Conner
Matt Roth
Character not listed
Danielle Harris
Molly Tilden
Brian Kerwin
Character not listed
Charlayne Woodard
Character not listed
Wings Hauser
Character not listed
Lori Tan Chinn
Iris
Mara Hobel
Character not listed
Joseph Gordon-Levitt
George
Stephen Dorff
Character not listed
Jared Rushton
Character not listed
Melora Walters
Character not listed
Fred Willard
Character not listed
Debra Mooney
Character not listed
Stan Freberg
Character not listed
Carl Franklin
Character not listed
Colleen Camp
Character not listed
Kathleen Freeman
Character not listed
Jay O. Sanders
Ziggy
John Randolph
Character not listed
Doug Fieger
Character not listed
Liz Georges
Character not listed
Elizabeth Franz
Character not listed
William Sadler
Character not listed
Heather Matarazzo
Character not listed
Michael Des Barres
Character not listed
Lee Garlington
Character not listed
Dan Butler
Character not listed
Luke Edwards
Character not listed
Kathryn Joosten
Character not listed
Morgan Fairchild
Character not listed
Mariel Hemingway
Sharon
Danny Masterson
Jimmy
Michael Dempsey
Character not listed
Tristan Tait
Character not listed
Phil Leeds
Character not listed
Jeremy Roberts
Character not listed
Mo Gaffney
Astrid Wentworth
Stella Butler
Nurse Stella
Zoe Perry
Little Jackie
Danny Gans
Character not listed
Madge Sinclair
Character not listed
Lenny Wolpe
Character not listed
Taylor Fry
Character not listed
DeeDee Rescher
Character not listed
Bob Denver
Character not listed
June Lockhart
Character not listed
Tobey Maguire
Character not listed
Pat Crowley
Character not listed
Don Keith Opper
Character not listed
Joe Grifasi
IRS Office Supervisor
David Tyree
Character not listed
Mikey Robins
Character not listed
Elya Baskin
Character not listed
Jack Blessing
Character not listed
Judith Hoag
Character not listed
Belita Moreno
Character not listed
Alyson Hannigan
Character not listed
Patrika Darbo
Character not listed
Troy Slaten
Character not listed
David Strickland
Character not listed
Mitzi McCall
Character not listed
David Crosby
Character not listed
Tom Virtue
Character not listed
Shecky Greene
Character not listed
Ed McMahon
Character not listed
Fabio
Character not listed
Anthony Geary
Character not listed
Bert Parks
Character not listed
Ahmet Zappa
Character not listed
Robert S. Woods
Character not listed
Jeff Corey
Character not listed
Timothy Carhart
Character not listed
Chan Kinchla
Character not listed
Abraham Benrubi
Teenage Dan
Sally Kirkland
Character not listed
Todd Field
Character not listed
Cleavant Derricks
Character not listed
Jack Murdock
Character not listed
Danton Stone
Character not listed
Bob Odenkirk
Character not listed
Dann Florek
Principal Hiller
Jenny Beck
Character not listed
David Lascher
Character not listed
Lisa Banes
Character not listed
Jeannetta Arnette
Character not listed
Marlo Thomas
Character not listed
Lawrence Hilton-Jacobs
Character not listed
Jim Turner
Character not listed
Ann Wedgeworth
Character not listed
Frances Fisher
Character not listed
Robert Harper
Character not listed
Susan Krebs
Character not listed
Peter Jason
Character not listed
Ellen DeGeneres
Dr. Whitman
Vicki Lawrence
Phyllis Zimmer
Jenna Elfman
Character not listed
Amzie Strickland
Character not listed
Stephen Lee
Character not listed
Mark Blum
Character not listed
Traci Lords
Character not listed
James Lew
Character not listed
Gary Bayer
Character not listed
Lynne Thigpen
Character not listed
David Greenlee
Character not listed
Dabbs Greer
Character not listed
Edie McClurg
Character not listed
Jean Speegle Howard
Character not listed
John Popper
Character not listed
Judy Gold
Character not listed
Brad Garrett
Character not listed
Russell Johnson
Character not listed
Clint Ritchie
Character not listed
Rebecca Schull
Character not listed
Arianna Huffington
Estree Longet
Debbie Reynolds
Character not listed
Bill Maher
Character not listed
Tom Amandes
Character not listed
Jeff Garlin
Character not listed
Loretta Lynn
Character not listed
Dawn Wells
Character not listed
Leonardo DiCaprio
Darlene's Classmate
Annie Abbott
Character not listed
Chris Tucker
Character not listed
Terri Treas
Character not listed
Eric Christmas
Character not listed
Fred Thompson
Character not listed
John Loprieno
Character not listed
Scott Burkholder
Character not listed
Stephen Root
Character not listed
Nigel Gibbs
Character not listed
Ashley Johnson
Character not listed
Red Buttons
Character not listed
Sharon Stone
Character not listed
Mike Pniewski
Character not listed
Pat Harrington Jr.
Character not listed
Florence Henderson
Flo
Ed Asner
Character not listed
David Sage
Character not listed
Eric Allan Kramer
Character not listed
Pat Bullard
Character not listed
Randall Slavin
Character not listed
Alexis Arquette
Character not listed
Romy Rosemont
Character not listed
Tony Curtis
Character not listed
Norm Crosby
Character not listed
Gracie Harrison
Character not listed
David Dunard
Character not listed
Thomas Kopache
Character not listed
Bob Nickman
Character not listed
Ed Begley Jr.
Character not listed
Joanna Lumley
Patsy Stone
Jerry Springer
Character not listed
Tom McTigue
Doctor
Erick Avari
Prince's Assistant
Jim Varney
Prince Carlos
Tammy Faye Bakker
Character not listed
Jonathan Emerson
Character not listed
Ken Kells
Character not listed
Andrea Marcellus
Character not listed
Christy Martin
Character not listed
Todd Oldham
Character not listed
Dana Gould
Chip
Garrett Hazen
Andy Harris
Kent Hazen
Andy Harris
Ronald E. House
Werner
Dina Merrill
Doris
Grinnell Morris
Skip
Cole Roberts
Jerry Garcia Conner
Iqbal Theba
Dr. Bakshi
Hillary Tuck
Kiki
Callan Farris
Kazim
Molly David
Woman in Coffee Shop
Brent Pope
Valente
David Mendenhall
Clerk (uncredited)
Rhea Seehorn
Carrie
Alan Washnevsky
Samir
Stevie Sterling
Stripper (uncredited)
Jonathan Mangum
Flip
Andi Chapman
Denise the IRS Information Clerk
Mark Lowenthal
Ed the IRS Office Clerk
Monty Hoffman
Man in Line
Rick Hall
Character not listed
Judy Kain
Character not listed
Jodi Long
Woman in Line
Stephen Prutting
Character not listed
Byron Batista
Character not listed
Jazzmun
Diana Ross
Sara Rue
Teenage Roseanne
Robin Greer
Customer #1
Jennifer Saunders
Edina Monsoon
Kevin Dunn
Burt
Eric Dane
Bellhop
Adilah Barnes
Anne-Marie Mitchell
Judith Jordan
Secretary Miss Carrie
Travis Weaver
Ralph
Justin Isfeld
Character not listed