On screen
Cast
50 credited performers
John Travolta
James
Kirstie Alley
Mollie
Olympia Dukakis
Rosie
George Segal
Albert
Abe Vigoda
Grandpa
Bruce Willis
Mikey (voice)
Twink Caplan
Rona
Artwork unavailable
Jason Schaller
Mikey
Artwork unavailable
Jaryd Waterhouse
Mikey
Artwork unavailable
Jacob Haines
Mikey
Artwork unavailable
Christopher Aydon
Mikey
Joy Boushel
Melissa
Don S. Davis
Dr. Fleischer
Artwork unavailable
Louis Heckerling
Lou
Brenda Crichlow
Secretary
Artwork unavailable
Andrea Mann
Salesgirl
Artwork unavailable
Douglas Tuck
Cab Stealer
Alex Bruhanski
Street Worker
Artwork unavailable
Casey Grant
Admitting Clerk
Artwork unavailable
Oscar B. Ramos
Hospital Worker
Aurelio Dinunzio
Orderly
Artwork unavailable
Jeff Irvine
Admitting Doctor
Artwork unavailable
Shirley Barclay
Nurse
William B. Davis
Drug Doctor
Artwork unavailable
David Berner
Mr. Impatience
Jerry Wasserman
Mr. Anal
Artwork unavailable
Daliah Novak
Carrie
Artwork unavailable
Zena Darawalla
Lupe
Nicholas Rice
Harry
Neal Israel
Mr. Ross
Blu Mankuma
Director
Artwork unavailable
William Britos
Home Orderly
Dee Jay Jackson
Burly Orderly
Artwork unavailable
Ida Berner
Lady
Artwork unavailable
Bea Cartmell
Lady
Artwork unavailable
Eleanor Maines
Lady
Mollie Heckerling
Little Girl
Artwork unavailable
Ryan McIntosh
Little Boy
Gerry Bean
Pilot Friend
Deryl Hayes
Pilot Friend
Enid Saunders
Ester
Artwork unavailable
Nicole Stevens
Silly Baby
Artwork unavailable
Christy Smith
Baby Megan
Artwork unavailable
Sabrina Bailey
Sand Box Baby
Artwork unavailable
Farah Abassi
Chatting Baby
Artwork unavailable
Amber Brownmiller
Blowing Kiss Baby
Artwork unavailable
Ariel Perryman
Nursery Baby
Artwork unavailable
Nigel John Crowe
Nursery Baby
Artwork unavailable
Michael Joseph Materi
Nursery Baby
Joan Rivers
Julie (voice) (uncredited)