On screen
Cast
17 credited performers
John Barrymore
Sherlock Holmes
Roland Young
Dr. Watson
Carol Dempster
Alice Faulkner
Gustav von Seyffertitz
Professor Moriarty
Louis Wolheim
Craigin
Artwork unavailable
Percy Knight
Sid Jones
William Powell
Forman Wells
Hedda Hopper
Madge Larrabee
Reginald Denny
Prince Alexis
Artwork unavailable
Peggy Bayfield
Rose Faulkner
Lumsden Hare
Dr. Leighton
Anders Randolf
James Larrabee
Robert Schable
Alf Bassick
David Torrence
Count Von Stalburg
Artwork unavailable
Albert Bruning
Baron Orlonieff
Robert Fischer
Otto
Artwork unavailable
Jerry Devine
Billy